We run Transforce HT on the F350. Its on a road 90% of the time and never in mud.
I have customers that are running the Transforce AT and like them for a more aggressive tread but still nice on the road.
I personally like the Dueller AT revo II tires in that size. Every set I've sold the customers really like them. I ran the previous version of that tire on my 1/2 ton chevy and loved them.