Three Floyds Brewing in Munster has great beer and great food, take the Calumet Ave exit off of 80/94 and go south, maybe 10-15 minutes down on the west side of the road.
Another good spot is in Valpo called the Industrial Revolution, on Rt 30 (Head towards Valpo and you won't miss it).
There's also a Tilted Kilt in Merrillville on 30. There's pretty much a little bit of everything in the Rt30/I65 corridor.
I live in the region, work in Merrillville. My tip would be to stay south of 80/94 as much as you can.