had the same thing happen to me going over a bridge in cincinnati at 65 mph. broke 3 of the studs off, 2 bent ones left. The tire left the trailer, literally bounced over the car behind us, bounced once more then over the side of the bridge and 75 feet down. tore the fender to shreds.
I had just replaced my old rusty chrome rims with shiny new alloy rims. apparently that one had loosened up and I didn't notice. It was a mess.
Luckily it was on the way home from vacation, not on the way there. FYI - MC trailers don't work very well on the typical flatbed tow truck. pretty sketchy operation.